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Every man likes to be confident in any sphere of his life no matter whether it concerns his work, family or private life. And when something goes wrong in one of these spheres it impacts the rest. That’s why there is no wonder that problems in sexual life can not only destroy relationships and leave a man without joys of life; its bad influence can sink into every sphere of life making a man feel unconfident and depressed.
You can ask what we are talking here about. We are talking about health problem which is not easy to discuss but which can’t be left unattended as it touches lots of men of different age, race and social position and is called impotence. And if you’ve found enough courage to admit you are suffering from it here is comforting information for you: impotence can and must be fought. You can enjoy your sexual life with Cenforce – a new medication dealing with the problem of erectile dysfunction by relaxing muscle tension in the genitalia area and widening blood vessels in penis so that the blood pressure can cause erection.
So if your sexual life faces the problem of impotence don’t panic and give up: now you can easily order Cenforce online and forget about your troubles once and for all.
Study Design and Setting
A cross-sectional, facility-based study was carried out among male clients visiting community pharmacies in Gondar, North-West Ethiopia. Gondar lies about 738 km from Addis Ababa, the capital of the country. At the time of data collection, the town had 20 pharmacies and 34 drug stores. According to national census projections from 2007, the total population was approximately 249,851, with a male-to-female ratio of about 1.5:1. The study period was from March 20 to May 10, 2017. Source Population All adult men in Gondar who used Cenforce for improving sexual function. Study Population Male Cenforce users meeting the inclusion criteria and visiting local community pharmacies during the study period. Sampling Technique All eligible Cenforce users who were available during the study period were included; therefore, no separate sample size calculation was required. Researchers approached all pharmacies in Gondar, but only seven granted permission for data collection. Drug stores were excluded since the sale of phosphodiesterase inhibitors like Cenforce is prohibited by Ethiopian law, although unconfirmed reports suggested illegal sales. Inclusion and Exclusion Criteria Inclusion: Men aged 18 years or older who voluntarily participated in the study and had used Cenforce. Exclusion: Users who began taking Cenforce less than six months before data collection. Study Variables The dependent variable was the recreational use of Cenforce, analyzed in relation to independent factors such as age, marital status, partner status, education, occupation, religion, use of illicit substances, and duration of Cenforce use. Data Collection Data were obtained through a structured, self-administered questionnaire originally written in English, then translated into Amharic and back-translated to maintain consistency. The tool consisted of 36 questions divided into three sections: (1) socio-demographic and clinical characteristics, (2) general perceptions, and (3) patterns of Cenforce use. Two trained data collectors supervised the process. Data Quality Control Data collectors received one-day training covering study objectives and procedures. A pilot test was conducted on five Cenforce users from two randomly selected pharmacies. Based on the pretest results, some questions were simplified or removed. Those participants were not included in the main study. All collected forms were checked daily for accuracy and completeness before data entry.
Data Management and Analysis
Data were analyzed using IBM SPSS version 20. Descriptive statistics were presented in tables. Binary and multivariable logistic regressions were applied to determine associations between variables. Factors with p-values <0.05 in binary analysis were included in multivariable analysis, and variables with p < 0.05 and 95% confidence intervals were considered significant predictors of recreational Cenforce use.
Operational Definitions
Recreational use: Taking a drug to enhance sexual performance without medical necessity.
Abuse: Prolonged or excessive consumption of Cenforce.
Ethical Approval
Ethical clearance was granted by the Ethical Review Committee of the School of Pharmacy, University of Gondar (approval no. SoP 826/09). Before participation, all subjects received full information about the study and gave verbal consent. No identifying data were collected, and all responses were treated confidentially.
RESULTS
Socio-Demographic Profile
A total of 65 men participated. The mean age was 37 years (range: 22–67). More than half (52.3%) were married, and 41.5% had completed secondary school (grades 9–12). Employment was reported by 36.9% of respondents, while 64.6% identified as Orthodox Christians.
Sexual Behavior
Most participants (58.4%) admitted to having engaged in unsafe sexual practices at least once. Sixty percent reported one stable partner, whereas 40% had occasional or multiple partners. Concomitant substance use was frequent: 63.1% consumed alcohol with Cenforce 200mg, 36.9% smoked cigarettes, and 23.1% reported khat use.
DISCUSSION
A notable observation in this and similar studies was the high rate of Cenforce acquisition without medical prescription. In the present findings, most respondents reported purchasing Cenforce as an over-the-counter (OTC) medication. Comparable results were documented in Ethiopia and in a web-based study conducted in the United Kingdom, Germany, and Italy. The latter identified embarrassment when discussing sexual health with physicians and the perception of lower cost as key factors influencing non-prescription acquisition of PDE5 inhibitors. Such easy access can result in inappropriate self-medication, higher incidence of adverse effects, and potential dependency.
The main reasons for Cenforce use reported by participants were enhancement of erection sensation and penile rigidity. A study from Argentina produced similar results, identifying increased penile firmness, longer erection duration, higher coital frequency, and avoidance of sexual failure as common motives for PDE5 inhibitor use.
A significant portion of respondents admitted combining Cenforce with alcohol and illicit substances: alcohol (63.1%) was most frequent, followed by cigarettes (36.9%) and khat (23.1%). This pattern aligns with previous Ethiopian research, where alcohol, khat (Catha edulis), and tobacco were among the most widely used recreational substances, particularly among young adults. Combining Cenforce with such substances can create pharmacokinetic and pharmacodynamic interactions that may lead to severe side effects or even death. Studies have shown that illegal drug use can significantly modify Cenforce plasma concentrations, while cigarette or cannabis smoking may further alter its pharmacological exposure.
The most commonly reported adverse effects among Cenforce online users were dizziness and headache. Data from large-scale clinical trials confirm that headache and flushing are the most frequent side effects in patients treated with Cenforce. This can be explained by its vasodilatory action: Cenforce may reduce mean peak systolic and diastolic blood pressure by about 10/7 mm Hg, independent of dosage. Such hemodynamic changes can result in transient hypotension, causing symptoms like dizziness, flushing, and headache.
LIMITATIONS
As a cross-sectional study relying on participants’ self-reported data, findings may be affected by response bias due to the sensitivity of the topic. Additionally, the limited sample size could restrict detection of less common behavioral patterns and contribute to sparse data bias. Despite these limitations, the study was conducted in an under-researched area with no prior local evidence. It provides a baseline for future research and highlights the need for regulatory oversight concerning non-prescription sales and rational use of Cenforce.
CONCLUSION
Most male users of Cenforce reported taking it for recreational rather than therapeutic purposes. Short-term use (≤2 years) showed a strong association with non-medical consumption. The easy OTC availability of Cenforce, lack of professional guidance, and absence of monitoring were key contributors to misuse. Concurrent use with alcohol or illicit drugs was also common. These findings underscore the need for coordinated action among pharmacists, clinicians, and policymakers to promote responsible Cenforce use.
RECOMMENDATIONS
Health professionals—especially pharmacists—should actively counsel Cenforce users about correct dosage, timing, and potential side effects. Patients must also be informed of the risks of combining Cenforce 100mg with other drugs or alcohol and advised to limit its use to genuine medical necessity to prevent dependence and adverse reactions. Regulatory authorities should strengthen control over Cenforce and other PDE5 inhibitors, prohibit their sale outside licensed pharmacies, and ensure compliance with prescription-only regulations.
DATA AVAILABILITY
All data supporting the findings of this study are available from the authors upon reasonable request.
ETHICS STATEMENT
This research was reviewed and approved by the Ethical Review Committee, School of Pharmacy, University of Gondar (approval no. SoP 826/09). All participants provided written informed consent before inclusion.
AUTHOR CONTRIBUTIONS
All authors contributed to data collection, analysis, manuscript preparation, and final approval of the publication. Each author accepts full responsibility for the content of this work.
ACKNOWLEDGMENTS
The authors thank the University of Gondar for institutional support and express their gratitude to all participants for their cooperation and contribution to this research.
Cenforce Utilization
Most participants learned about Cenforce from friends (70.6%). Access pathways were often multiple; the majority (89.3%) reported obtaining Cenforce without a prescription (OTC). Overall, 43 men (66.2%) reported using Cenforce for recreational purposes (see Table 2).
Timing of intake varied: 61.5% took Cenforce about 30 minutes before sex, 20% whenever they anticipated sex, and 18.5% immediately before intercourse. Affordability and access were not major barriers: 84.6% considered the price affordable, and 67.7% said Cenforce was easy to obtain at community pharmacies.
Regarding duration of use, 50.8% had taken Cenforce for ≤1 year, 27.7% for 2 years, and 21.5% for >2 years. Most respondents (84.5%) reported no social pressure or stigma, and 83.1% indicated willingness to use Cenforce again. Preferred formats for receiving information were written materials (69.2%), radio/TV (33.8%), and audiovisual recordings (10.8%). The most frequently reported side effects were dizziness (69.2%), headache (49.2%), blurred vision (29.2%), prolonged erection time (9.2%), and stomachache (4.6%).
Factors Associated With Cenforce Online
Binary and multivariable logistic regressions examined predictors of recreational use (medical use treated as the reference). In binary analysis (P < 0.05), duration of use, partner status, marital status, and age were significant. After adjustment, only duration of Cenforce use remained significant (P < 0.05): men with <2 years of use were more likely to report recreational use than chronic users (>2 years). Specifically, users with <1 year of exposure had markedly higher odds (AOR = 34.086; 95% CI 2.90–401.37), and those with ~2 years of use also had elevated odds (AOR = 21.42; 95% CI 2.10–218.82) compared with >2-year users (see Table 3).
Some respondents reported medical indications for Cenforce online: diabetes mellitus (27.1%), heart disease (9.2%), hyperlipidemia (4.2%), and relationship issues linked to stress and poor communication (3.1%).
DISCUSSION
This study found widespread non-medical (recreational) use of Cenforce among younger men, aligning with findings from other settings where younger participants commonly use PDE5 inhibitors recreationally. Because erectile dysfunction is more prevalent at older ages and with chronic comorbidities (e.g., hypertension, type 2 diabetes), younger users may rely on Cenforce primarily to enhance performance rather than to treat ED. Recreational use was more common among participants with multiple sexual partners, consistent with reports suggesting an intent to prolong sexual activity or to boost confidence.
Peers were the dominant information source about Cenforce, a pattern also noted elsewhere (friends, internet, sex shops). Seeking guidance outside healthcare settings can increase risks—such as priapism, drug–drug interactions, or contraindications related to comorbidities—especially when Cenforce is combined with other substances. Visual disturbances were among the reported adverse effects, echoing known safety concerns for this class (PDE5 inhibitors).